Should I let me father-in-law smoke if it means he'll take his pills?
I have seen this before -- you're not alone in bargaining with the patient to do things that are GOOD for them. It doesn't seem to make sense. However, there are many considerations behind it: Could they clinically depressed? Are they fatigued or in pain? Have they given up on a cure or on life in general? Often, if you can get these conditions addressed, patients have a renewed sense of life and start to help themselves.
From what you say, it sounds like his quality of life is not so great: difficulty breathing, walking with a walker, extended hospital stays. Have you had a discussion with him on how he feels about all of this? I would encourage you to ask him what else he'd like to accomplish in his life and how you can help him do that. Encouraging him to keep living may be difficult if he doesn't want to.
I know these are serious discussions, but you need to understand where your efforts are best utilized. Maybe it's not the right thing to do to force him to take meds. It's your job to understand his needs and give him comfort. While I don't condone smoking, it may relax him and counter some cravings, which will add to his quality of life. At this stage, that may be the best way you can help him.
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