Are there any long term effects due to M.O.P.P. chemotherapy which could effect your cardiovascular system?

Greg47 asked...

Are there any long term effects due to M.O.P.P. chemotherapy which could effect your cardiovascular system?

Expert Answer

Senior Editor Melanie Haiken, who is responsible for Caring.com's coverage of cancer, general health, and family finance, discovered how important it is to provide accurate, targeted, usable health information to people facing difficult decisions.

The chemotherapy regimen for Hodgkin Disease known as MOPP does have several effects on long-term health but danger to the cardiovascular system isn't one of them. MOPP causes permanent sterility due to the Mustargen (the "M" in MOPP). It also has a 3 percent chance of leading to a secondary cancer, acute myelogenous leukemia. For this reason many oncologists choose an alternative chemotherapy regimen, ABVD, for Hodgkin disease when possible. Radiation treatment to the chest carries a risk of damage to the cardiovascular system, but the MOPP chemotherapy regimen should not.