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Can Plavix and ibuprofen be taken together?

3 answers | Last updated: Apr 05, 2015
VirgeMy asked...

Can Plavix and ibuprofen be taken together?


Dr. Jennie Powell is a certified geriatric pharmacist and owner of Right at Home of Morgantown, WV, an in-home care and assistance agency. As...
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Jennie Powell answered...

While not completely contraindicated (meaning it's not an absolute rule), there are many warnings about the use of Plavix with nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen.

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risk is bleeding"”NSAIDs are known to cause ulcers and other disruptions of the gut, and Plavix works by inhibiting clotting. So a minor irritation of the lining of the stomach, which is often caused by NSAID use, can quickly become a dangerous bleed when the NSAID is coupled with Plavix.

Acetaminophen, known to most as Tylenol, is the preferred pain reliever for anyone on a "blood thinner" such as Coumadin or Plavix. As with all medications, be sure to let your doctor know what over-the-counter medications you are taking. If you need pain relief beyond that provided by acetaminophen, your doctor can suggest alternatives that are safer than using NSAIDs.


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MPuma48 answered...

Plavix(http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000040) is a medication that inhibits the formation of blood cots. Ibuprofen(http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000598) is a NSAID (nonsteroidal anti-inflammatory drug). Both medications can increase the chance that the patient may have bleeding issues. Therefore the potential that Plavix and ibuprofen (And other NSAIDs) taken together can increase the risk of severe bleeding to dangerous levels means that these two drugs should usually not be taken together. You should consult closely with your doctor about the risks and potential benefits from combining the two medications.