Doctors typically suggest taking vitamin B6 -- sometimes with folic acid -- before and during chemo to prevent and treat neuropathy (numbness, tingling, and pain caused by nerve damage). Chemo agents can cause a B6 deficiency, which is associated with neuropathy symptoms. However, if the B6 doesn't seem to be working, try taking a B-vitamin combination that includes B1, B2, B12, and folic acid instead. Some cancer patients find this more effective because too much of one B vitamin can lead to a deficiency in others.

Sources

Cancer message boards

The National Coalition for Cancer Survivorship