The cost of Januvia is pretty reasonable for everything that it does, each of the pills is around $4.36, but that is just for one. Depending on how often you need to get your prescription refilled, the cost of these small pills can really start to add up. With the average amount of refills, you should end up paying around $150.00 for Januvia. When compared to other brands that are similar, the cost of this is around the same. Make sure to follow the doses that are instructed on the prescription and you won't have to pay more to buy more pills.