What would cause total weakness in limbs?

A fellow caregiver asked...

My father is 57. He had a carotid endarterectomy about one month ago. He also had two strokes the fourth day after surgery. His doctor hospitalized him for fifteen days more. He is okay now but has started to experience total weakness and use of his body parts. His blood pressure is still fluctuating up to 180 even though he's walking and doing daily work. I don't know the cause and would appreciate any advice.

Expert Answer

James Castle, M.D. is a neurologist at NorthShore University HealthSystem (affiliated with The University of Chicago) and an expert on strokes.

Stroke after carotid endarterectomy is a fairly common complication of the surgery.  However, it should almost always affect only one side of the body.  There are a few exceptions to this.  Sometime, the carotid artery on one side of the neck will supply blood to both sides of the brain, either because of an inborn variant of artery anatomy, or because of an unhealthy artery on the other side of the neck.  Another exception would be if the stroke was in an entirely different artery from the site of the surgery.

It sounds to me like the first order of business here should be to find out whether or not the post-operative strokes were on one or both sides of the brain, and whether they were in the artery where the surgery was performed.  Your surgeon, and probably your internist, should know the answer.

If the strokes are only on one side of the brain, in the territory of the surgery, then it does not make sense that your father would have weakness on both sides of the body, since each side of the brain controls the opposite side of the body.  In this scenario, other causes of weakness would have to be looked into.  These would include such issues as 1) side effect to a medicine - particularly cholesterol or blood pressure medicine, 2) infection such as pneumonia or urinary tract infection, or 3) post-stroke sedation.