Not a geriatrician! Not even an M.D., but Harvard educated, and have cared for my mom for seven years now. And, I actually DID assist her in transforming herself from a drooling, uncommunicative, knife wielding, person with dementia (which she was under my father's care) to her very BEST self - including, after two years under my care - being able to PASS A COMPETENCY TEST. So, I know more than" a few things" and perhaps a tad more than the regular caregiver.
It is NECESSARY to rely on M.D.s, but always best to go to them fully INDEPENDENTLY informed. I research everything myself, so when I walk into an office the doctor knows I am WITH him or her or even AHEAD of him or her at all times.
There are websites online which allow you to calculate drug interactions/ side effects. Just google "drug interactions" and multiple sites will come up. Check them out until you find one that feels user-friendly to you. The internet is a source of information, BUT NOT ALL OF IT IS OF VALUE. Don't forget that. Cross check everything multiple times across multiple sites.
I still maintain that to blame Seroquel for your mom's symptoms IS "pointless" BUT it is NOT POINTLESS to investigate other causes, INCLUDING Seroquel "in combination with other meds" she is on... Research is critical, but all research we read is based on someone else's trial and error testing - so do your own trial and error! Why is she on the drug in the first place?
My own mother is on Seroquel (HUGE dose, by the way,) Namenda, Trazodone, Zoloft, daily megavitamin, CoQ10, Fish Oil, 81 mg aspirin regimen, (reduces stroke etc.) the new 23 mg Aricept, and megadoses of both vitamins D and comprehensive B-Complex. She exercises daily and can still read, though sometimes she needs help understanding what she reads. She is losing the ability to make intelligible conversation, but can still talk (and walk four miles...)
She EATS LIKE A HORSE! She is fed CONSTANTLY while awake. And, she sleeps a lot! But after she has had all the sleep she "needs" she is higher functioning when awake. Many people try to force a normal daily rhythm on these folks, which I have found to be a mistake. She does best when she lives a "half-life" - that is all she can handle. However, the quality of her time in her reduced periods of wakefulness is greatly improved. I believe that, like any brain, the AD brain needs REST - and a great deal more of it than a normal brain - to function at its highest level.
My mother has been diagnosed with AD since 2004, but has been symptomatic since 1998... I took on her care after she pushed my father down the stairs to his death in 2004. Currently, I am making preparations to put her in care, as she needs increasing help with physical care, and I am unable to manage providing it. Also, as she drifts further into her world of the past - into her efforts to RECONCILE her past - I believe she will benefit most by being in the company of others like herself. It absolutely torments her to see my college aged sons leading lives she herself desperately wants a chance to relive...
So, I'm sorry! Not a geriatrician... ;- ) Though, believe me when I tell you - you are not the first to think so - or to ask! All the best to you.