Crestor treats high cholesterol, a condition that is only one risk factor for heart disease and strokes. Stopping it cold turkey won't cause you to have a heart attack or stroke or immediately increase your risk of having one, so you shouldn't worry about any kind of tapering off program. If your doctor thinks you need the drug, you shouldn't stop taking it without his or her supervision, though. You will probably want to go on something to replace it. There are other statins available, and there are drugs of other types that some think are just as useful in controlling cholesterol. I would look into some of the health food store alternatives, too.