Trazodone is an oral antidepressant that is prescribed for many different uses, both on- and off-label. Like other drugs of its kind, it combats anxiety and is used to treat
many disorders like obsessive-compulsive disorder, panic attacks, and the like. Restless Leg Syndrome (RLS) is a constant desire to move one's legs to avoid discomfort. Like 'scratching an itch' that never subsides, sufferers of RLS are often troubled by an inability to sit still and maintain a restful position. Trazodone has not been shown to cause RLS. In fact, it is often prescribed for RLS sufferers (often those who suffer from other anxiety-related issues as well). Depending on its effect on the individual, RLS can be helped or worsened by Trazodone, but Trazodone is not the cause of RLS.