Shingles, or herpes zoster, is caused by the same virus responsible for chicken pox. When a person gets chicken pox, the virus remains in a latent stage in the body,
and may reappear as shingles years later. Fatigue is a common symptom of shingles, along with other flu-like symptoms such as fever and chills. Shingles can be quite painful--it affects the nerves, and the pain or tingling can last after the rash has dissipated (this condition is known as post-herpetic neuropathy). Dealing with this pain, especially in the long-term, can cause a sufferer to feel quite tired and fatigued. If you suspect that you have shingles, see your doctor. There are antiviral drugs that can help to control the virus and lessen the severity. Be sure to avoid anyone who has not had the chicken pox, and especially stay away from newborns and pregnant women.