My daughter suffers from hives so I was interested in the possible link between bone cancer and mastocytosis, however I think I may be barking up the wrong tree.
reason I was confused was because mastocytosis is caused by the presence of too many mast cells in the body. And those mast cells, made in the bone marrow, produce histamine, which is involved in allergic reactions. Most cases of mastocytosis are only skin deep, causing itching, hives, and flushed skin. That’s why we sometimes take antihistamines, to control the histamine and get rid of our allergies.
Systemic mastocytosis, which involves the internal organs, is much more severe and that’s the kind that may be associated with cancer. There IS a link between systemic mastocytosis and bone marrow cancer, such as leukemia. Mast cell leukemia is a form of systemic mastocytosis where more than 20 percent of bone marrow cells are mast cells. Fortunately it’s very rare. And having allergies does not put you at risk of getting it!