If you or a woman you know has early stage breast cancer that's HER2-positive, she needs to know about some new research published yesterday in the Journal of Clinical Oncology.
An early stage tumor that's as tiny as one centimeter or smaller still has a high risk of deadly recurrence if it's HER2-positive, new data show.
Researchers from the M.D. Anderson Cancer Center reviewed recurrence data on breast cancer patients whose tumors were one centimeter or smaller -- typically considered to present a very low recurrence risk. (See size chart; one cm is about the size of a black-eyed pea.) What they found was that if a woman's tumor, no matter how tiny, was HER2-positive, her 5-year recurrence rate was 23 percent -- almost one in four.
Led by Ana Gonzalez-Angulo, MD, the researchers analyzed the center's breast cancer research database, which contained data on 965 women whose tumors were less than one centimeter when diagnosed, and who did not receive treatment with Herceptin... Read more




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