Is TDM-1 a Miracle Drug for Advanced Breast Cancer?

I too have HER2+ beast cancer that met. to my liver, for 4 years. I went through all of the treatments, carbo, taxotere,taxol, herceptin and others that I can not remember. Cyber knife surgery with radiation, liver surgeries, I have been through everything. I am now taking the T-DM1 drug, I have to travel to get it. The stress this puts on a stage 4 patient and their families, to me is very un-necessary. If you qualify, you should be able to get the drug through your doctor, at home, where you are comfortable, your doctor can follow guidelines and report any issues. It really saddeneds me to have to put my family through this in the first place, now this added stress. I wish drug companies would really reconsider how trials are run. Without us, they would not have any trials. This drug has been in trails for 13yrs. I saw the news reel with Phil and Lorraine from Boston, she is 100% correct. It is very stressful. I am very happy that she has grandchildren and is here to enjoy and love them. We are waiting to meet our first grandchild in June 2011. Hopefully with T-DM1, I will meet mine.

I'm so glad about your wife! My best wishes to you! I'm a candidate for a clinical trial with TDM1 and your comment gave me strength, faith and confidence! I ask god for a miracle and I think I will get it!

My mom is ER+/HER2 negative/neu (HER-2/neu) . . . would this work for her at stage 2, 3 or 4??? It sounds like we want this drug over the Herceptin they are wanting to try. I want to implement the best possible treatment and after discussing this with my mom, we are more than likely gonna ask our oncologist about this "super Herceptin" of sorts. We are ABOUT to start a trial w/ Herceptin and about 4 other meds... so if we can do something different... I am just curious about those with NEGATIVE HER2 where estrogen is believed to be the majority of the cause. Thank you SOO MUCH for posting this information.

hiiii.... im dr.yaser from saudia arabia... my mother has acute meyloid leukemia on palliative chemotherapy.. is it possible to use this new medicine on my mother case? and if it is.... how can i get it... thank you.....

My wife has breast cancer that's HER2-positive. Starting in her breast it came back in her liver (3 spots) and her spine (2 spots) and her hip bone. Then in April 2 tumors were found in her brain. After 2 years of several kinds of chemo and radiation her poor body was so worn down she could walk to the mailbox and back and had to take a nap. Her oncologist was going to keep her on the chemo drugs until she just couldn't go anymore. We decided to get a second opinion and the new oncologist recommended that she begin a treatment of TDM1. Last week we got the last of all the test and there is no sign of cancer in her whole body. First, I praise the Lord Jesus Christ and secondly I thank God for TDM1 and pray daily that the drug will get okay-ed by the FDA soon. It is a miracle drug. alight

so glad to hear the good news..now my mom had a conservation surgery and recieved chemo and radio-therapy, then 3 years later she got another tumor in the same breast which was HER2+ and had a mastectomy then chemo + herceptin...her scans seem to be good and thank GOD clear... i'm asking now is there anything we could do 2 stop the recurrences? any medication or regime she should follow?? also how do we reverse the side-effects of taxotere such as neuropathy? thanks!

io sono una her 2 + metastatico refrattaria alla chemio tch (taxotere, carboplatino, herceptin) attualmente in cura con herceptin e vinorelbina. ho metastasi nei vasi linfatici del torace, puo' essere efficace per me il t-dm1? ed e' possibile effettuarlo in italia? grazie