Scientists have a growing understanding of which Alzheimer's patients are more likely to outlive their peers with the disease. In 2004, a University of Washington study funded by the National Institute on Aging (a branch of the National Institutes of Health) identified several factors that influence life expectancy:
- Gender. Women in the study tended to live longer than men -- an average of six years after diagnosis, compared with four years for men.
- Age at diagnosis. People diagnosed with Alzheimer's in their 70s had longer survival times than those older than 85. The male-female difference shrank among those who were older when they first developed the disease. Newly diagnosed 85-year-old women in the study had a median life expectancy of 3.9 years, compared with 6 years for unaffected women of the same age. A man diagnosed with Alzheimer's at 85 had a life expectancy of 3.3 years in the study, compared with 4.7 years for a man of that age without the disease.
- Severity of symptoms. The more significant the impairment at the time of diagnosis, the shorter the probable number of years left. People over 85 who wander or have trouble walking, for example, are among those with the poorest survival rates.
Also showing diminished survival rates were study subjects who scored the worst on a commonly used memory and cognition (thinking skills) test, the Mini-Mental State Exam (MMSE).This test asks subjects to do a series of simple tasks, including answering questions about the date and place, remembering three objects, and counting backward by increments. An MMSE score refers to the number of correct answers given out of a total of 30. A five-point drop in score over the course of a year was linked to decreased survival rates among patients in the study.
However, simply scoring poorly doesn't mean a person doesn't have long to live. Sometimes a poor MMSE score is the first indication of cognitive trouble, which may indicate the very start of Alzheimer's and therefore a longer life expectancy than predicted for someone who's had memory problems for years.
Note: There are multiple factors that can influence an MMSE score. The test is not an Alzheimer's diagnostic test -- in fact, no such test exists.
- Other health problems. Survival was also poorest among those aged 85 and older who had histories of diabetes, congestive heart failure, or a past heart attack.
What often happens in people with Alzheimer's disease is that their general health suffers when, in the late stages, they forget or find it difficult to eat, don't sleep properly, lose motor skills, and develop bedsores. This sets the stage for infection, such as pneumonia, or the worsening of other chronic ailments. It's those factors, not the Alzheimer's disease itself, that ultimately result in most deaths.
Bear in mind that the facts above represent group averages. Your parent, of course, is an individual with a unique health history. And Alzheimer's is a disease whose pace can vary widely from person to person. Still, having even a rough sense of what to expect can provide a glimmer of useful light at a difficult time.
What influences Alzheimer's longevity?


When people read the TITLE of this article, it leads them to believe that they will be getting an answer to the question. The text of this article should state BRIEFLY, clearly and succinctly: "THERE IS NO ANSWER TO THE QUESTION." This article simply states what anyone in the trenches already knows, and it offers ZERO useful information for Newcomers. NO ONE who comes to this site has time for useless generalities... I really detest these useless articles.
I am a dementia practitioner and have been asked this question on many occasions. There is no real answer as there is only one person who really knows and that is our great creator. Every person is an individual as you mentioned. I have had a woman in the same end stage condition for six years and she just passed a month ago. You just don't know. The caregiver is the person who has the most stress . unfortunately there are no real answers to the expectancy in which a person with AD will have, which your article does suggest. Thank you for your article there are some very good points.
My heart goes out to anyone who must face this disease and watch it destroy your loved one. My mom was diagnosed in 2000, we initially thought she had had a stroke. An MRI ruled that out. She lived with me until I couldn't care for her anymore, about 2 years. I had to place her in a nursing home, where she fell and broke her hip and died with pneumonia 4 months later, in 2002. We tried all the meds that were on the market at the time and nothing seemed to even slow the Alzheimers down. The meds were all expensive and my mom (a widow) was living on a fixed income. It put a strain on our income as well. I quit my job to take care of her and we were depending on my husband's sole income. We don't regret our decision though. I hope and pray that medical science can come up with a cure, a prevention or at least a medicine that helps. My mother said, (when we were told that she had the disease) "There are lots of things that are worse than Alzheimers". I'm just glad that I don't know what that could've been. This was pure hell for all of us and I can't imagine a more cruel, helpless, disease. I love you mom and miss you every day!!
I hate this disease. my mother passed away 5 years ago. For 2 years it was so awful for her and myself as I was her caregiver. Had to place her in a group home. Fortunately a decent one. But did cost... Put me in the poor house. But, could not work a come home finding her on the floor. Having someone there for 10 hours a day too expensive and daycare just did not work out. Then she would be up alot at night. Just so awful. I'm still not over it. The best to all who have this disease.
The article mentions that the general health can suffer since your loved ones may have difficulty with eating and sleeping properly. Another important factor to maintaining health is closely monitoring any medication they take. If they are reliant on insulin for diabetes, for example, neglecting to properly medicate can dramatically impact health and therefore shorten life span.